By Reinhard L. Friede
I used to be gratified by means of the main favorable reception and large utilization bought via the 1st variation of this ebook. A decade appears a brief interval for a ebook on pathology, and but it witnessed many vital adjustments of suggestions, in addition to a powerful progress of information. the second one variation required wide reorganization. There are new chapters on mitochondriopathies, on peroxisomal illnesses and on spongy myelino pathies. significant revisions and new additions have been priceless in lots of chapters, for example these at the dysplasias of the cerebral and of the cerebellar hemispheres, that have been principally reorganized. The chapters on perinatal pathology have been reordered and reorganized to offer a extra logical series of prenatal, perinatal and postnatal lesions. the total textual content used to be labored over for brevity. A wealth of recent references was once additional with the. objective of staying abreast with the literature as much as summer season 1988. All refer ences have been double checked for blunders. My gratitude is going to Mrs. Gisela Ropte and Mrs. Cynthia Bunker for his or her untiring, diligent support. accordingly, this moment variation is an primarily rewritten textual content. strengthen within the prevention of human soreness relies on an intensive comprehend ing of the character of disorder. i am hoping that this article is going to stay of carrier during this behalf. maybe it might additionally mirror and foster the highbrow interest which makes the "reading of brains" so attention-grabbing an career. Gottingen, 1989 Reinhard L.
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Microscopic extravasations of blood may be seen in all portions of the brain, but their significance is doubtful. Hemsath and Canavan (1932) observed petechiae in 54 percent of one or two sections taken at random from the brain stem, and Hirvensalo (1949) found them in 37 percent of his cases but did not consider them of clinical significance. Craig (1939) observed major perivascular hemorrhages in only 6 of 126 cases, all of whom were larger children delivered at term under prolonged labor. Very young, aborted fetuses may show such hemorrhages with greater frequency, such as 63 of 65 (Solcher, 1968), including hemorrhages into the choroid plexus, ventricular walls and cerebral hemispheres.
Kinderheilk. 31: 165-372, 1927. : Morphologie und Entstehung der geburtstraumatischen Blutungen im Gehirn und Schadel des Neugeborenen. Z. Kinderheilk. 40: 427-474, 1925. : Die geburtstraumatischen Veranderungen des Zentralnervensystems einschlieBlich der Encephalitis congenita. Virchows Handbuch Spec. Path. Anat. Histol. XlIII3: 239-287, 1955. : Zur Neuroanatomie und Neuropathologie der Friihfetalzeit. Monogr. Neurol. Psychiat. 127: 1-78. Berlin-Heidelberg-New York: Springer 1968. Spears, R. , Hodgman, ].
Very young, aborted fetuses may show such hemorrhages with greater frequency, such as 63 of 65 (Solcher, 1968), including hemorrhages into the choroid plexus, ventricular walls and cerebral hemispheres. Residual Lesions. The various types of hemorrhages described in the present chapter appear to develop most often during a critical phase close to the infant's demise, so that acute hemorrhages are seen much more often than residual lesions. Only 5 percent of the subependymal hemorrhages in the present author's series presented as residual lesions.