By Sue Ellen Koehler Carpenter MD; John A. Rock Jr. MD
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Extra resources for Pediatric and adolescent gynecology
Fusion of the Labia Minora Fusion of the labia minora is often the sequela of infection or sexual abuse. However, congenital fusion apparently unassociated with these factors has been observed in siblings (220) and in more than one generation (221,222). Imperforate Hymen Ordinarily the central portion of the hymen is patent (perforate), thereby allowing outflow of mucus and blood. If the hymen is imperforate, mucus and blood accumulate in the vagina or uterus (hydrocolpos or hydrometrocolpos). An imperforate hymen is easily corrected by surgical incisions, preferably cruciform.
Genetics of oocyte depletion. In: Lobo RA, ed. Perimenopause. Serono symposia USA Norwell, Massachusetts. New York: Springer, 1998:36. 49. Simpson JL. Gonadal dysgenesis and abnormalities of the human sex 32. Ferguson-Smith MA, Sanoudou D, Lee C. Microdeletion of DMT1 at chromosomes: current status of the phenotypic-karyotypic correlations. 3 is the commonest cause of 46,XY females. Am J Hum Genet Birth Defects 1975;11:(4)23. 1998;63:A162. 33. McDonald MT, Flejter W, Sheldon S, et al. XY sex reversal and gonadal dysgenesis due to 9p24 monosomy.
A gene mapping to the sex- 14. Simpson JL, Christakos AC, Horwith M, et al. Gonadal dysgenesis determining region of the mouse Y chromosome is a member of a novel associated with apparently chromosomal complements. Birth Defects family of embryonically expressed genes. Nature 1991;346:245. 1971;7(6):215. 35 15. German J, Simpson JL, Chaganti RSK, et al. Genetically determined sex- 34. de Grouchy J, Gompel A, Salmon-Bernard Y. Embryonic testicular reversal in 46,XY humans. Science 1978;205:53. regression syndrome and severe mental retardation in sibs.